Glucosamine Hydrochloride (the chloride form of N-acetyl Glucosamine) is the newest and purest form of glucosamine, and the form now preferred by the medical profession for long-term use. When there is excess wear, more raw material is needed for repair of the joints and surrounding structures. If body chemistry is unbalanced, it may be that insufficient glucosamine is formed, which limits our ability to repair wear and damage. Equally, as we age, the enzyme glucosamine synthetase becomes less effective, which slows the rate of matrix repair. This is why healing is slower in the elderly. Glucosamine speeds regeneration. As long as your rate of repair keeps up with the rate of tissue loss, your bones and tissues will stay healthy.